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Ryan Neff

MD, PhD
Genomics, Data Science, and AI

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About Me

What I Do

I am a PGY-2 Internal Medicine Resident at The Mount Sinai Hospital in New York, NY. I recently graduated with a MD/PhD from the Icahn School of Medicine. I completed my doctoral research in the Bin Zhang Lab at the Mount Sinai Center for Transformative Disease Modeling.

My research interests are in improving our understanding of systems biology through multi-omic models. These are complex interaction networks that measure how DNA (genomics), RNA (transcriptomics), and proteins (proteomics) interact in the human body. Using statistical methods, large computers, and novel computational techniques, we are able to identify subtle differences between health and disease in these networks to discover new therapies to treat them. My research interests span many domains including cardiovascular disease, Alzheimer's disease, breast cancer, and digestive health. My eventual goal is to leverage personalized multi-omic models to bring precision medicine from the benchtop to the home for everyone.

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Harvard College, Class of 2013, Biomedical Engineering SB

Knowedge in several languages and technologies

Python R Javascript MySQL HTML5 / CSS3 JQuery Flask Twilio C / C++ Matlab Solidworks Ruby on Rails InDesign Illustrator After Effects

Inventor with 4 patents

See my patents on autonomous cars

Published scientific researcher

ORCID NCBI Bibliography ResearchGate

What matters to me

In my free time, I like to come up with new ideas to solve existing challenges, and translate them into new inventions, patents, and real-world products.

I think it's important to tackle problems from new angles of attack, and to maneuver your company so that your solutions can gain lift. I have helped many companies achieve their investment goals including 4C Medical, Atia Health, and Demeter so they can get off the runway. Currently, I'm interested in finding and investing in new opportunities in the medical and informatics space, even at the pre-seed/angel stage.

I also have many hobbies and like to ride bikes around the city, mess with electronics, and spend time with close friends and family. I also fly with the recently-formed Sinai Aerospace Medicine Club.

Winner of several hackathons and business competitions

Teaching assistant and tutor in data science

My Projects

Identifying Alzheimer's Disease Molecular Subtypes

RNA-seq and genetics of post-mortem brain biopsies of 364 patients with Alzheimer's.

Read our latest publication in Science Advances >

Get the data at Nature Scientific Data >

Suretify / ISMMS Student Health Check

IFTTT-like triggers for hospitals and discharge planners. Used for real-time COVID-19 tracking by over 3000 students and residents in the medical and graduate school.

See the COVID-19 Tracker >

Check out the award >

SuperNOVA

Differential coexpression network analysis on multiple subgroups.

Check it out >

Pollex Grasp

A wearable soft robotic assist device to help patients with hand disability to regain their grip.

Read the article at Harvard >

Maneuverable Catheter Wrist

Design of a strong yet flexible catheter tip for delicate cardiac surgery.

Read the report >

Demeter Health

An innovative mail-in test for a wide range of digestive symptom insights, powered by next-generation sequencing.

How does Harvard watch TV?

An in-depth network analysis of real-time streaming TV viewership at Harvard.

Check it out >

Sesame

An app to help your Amazon Alexa recognize your voice. Developed at TechCrunch Disrupt.

Check it out >

Some More Projects...

Curriculum vitae